Concrete, the most widely used construction material in the world, is largely responsible for the generation of construction and demolition waste (CDW). With the difficulty of final disposal of such waste and the increasing scarcity of raw concrete materials, become important to develop actions that could mitigate these problems. In this bias, we study the use of RCD as recycled aggregates in structural concretes. The aim of the present work is to verify the mechanical characteristics changes of concrete made with coarse and/ or fine recycled aggregate in relation to concretes made with natural aggregates (NA) only. For this, the natural and recycled aggregates are characterized and compared. The results indicate that the quality (absorption, specific mass, void index etc.) of recycled aggregates is lower than natural aggregates. Concretes were fabricated with 25% and 100% replacement of NA by CDW. These replacements were performed in the fine, in the coarse and in the two types of aggregates at the same time, totaling seven concrete mix design. The results point to the loss of performance (compressive strength, workability, Young's modulus, absorption, etc.) of concretes made from recycled aggregate, these losses are higher in cases where there is 100% substitution of the natural aggregate. However, these losses are in some cases relatively small, at around 15%. It is understood that, considering the possible environmental and financial gains, concrete with a 25% substitution are feasible and suitable for use as structural concrete.