Synthesis of Fe3O4 particles for applications in cancer treatments by magnetic hyperthermia.

Reference	Presenter	Authors (Institution)	Abstract
03-016	Fernanda Aparecida Sampaio da Silva	da Silva, F.S.(Universidade Federal Fluminense); Campos, M.F.(Universidade Federal Fluminense);	Malignant tumors are due to the disordered multiplication of the body's cells. Currently, a promising technique, magnetic hyperthermia, can provide the destruction of dysfunctional cells, preserving healthy cells. By means of this technique, it is possible to interrupt the growth of tumor cells by the point application of heat from magnetization / demagnetization of magnetic nanoparticles (Joule effect), when internalized by the bloodstream. The amount of heat generated depends on some parameters related to the nature of the magnetic material and the characteristics of the external magnetic field. In this work, Fe3O4 particles were synthesized by coprecipitation, coated with a polymer blend of polyethylene glycol polyethylene glycol and polyvinyl pyrrolidone (PEG / PVP). The resulting nanoparticulate powder was characterized by MAV, Mössbauer and FTIR techniques. The results of the characterizations indicate relevant values of magnetic saturation (72.1 emu / g), in addition the Mösssbauer and FTIR analyzes confirm the presence of magnetite in the synthesized samples.
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