Reference | Presenter | Authors (Institution) | Abstract |
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03-012 | Eliandra Sousa Trichês | Trichês, E.S.(Universidade Federal de São Paulo); Barbosa, L.(Universidade Federal de São Paulo); |
The bioceramics based on calcium phosphate are usually used in the orthopedic area, which aims to improve deficiencies due to aging, or even caused by injuries and fractures. Among this class of materials, hydroxyapatite (HA) and tricalcium phosphate (TCP) are the most studied due to its mineralogical composition, similar to that of bone tissues, and its properties, biocompatibility, bioactivity and osteoconductive capacity. Although, HA has good properties, it presents slow biodegradation, thus the development of composite scaffolds containing different amounts of HA and ?-TCP has been studied to obtain degradation rates more appropriate to bone regeneration. The scaffolds are defined as supports that serve as a substrate for cell growth, proliferation and differentiation. One of the processing methods for scaffolds production is the gelcasting of foams. This method is based on the introduction of organic monomers into an aqueous suspension of the ceramic powder, that by “in situ” polymerization produce a three-dimensional reticulate that consolidates the ceramic die after drying and sintering. Thus, this work aims to the production and characterization the HA/?-TCP scaffolds by the gelcasting method. The HA/?-TCP scaffolds presented 68.54 ± 3.80% of porosity and mechanical compression strength of 7.96 ± 1.85 MPa. The scaffolds’ macrostructure showed spherical and interconnected pores, with mean pore size of 242 ± 83 ?m, desirable for bon |
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