The high performance concrete is defined as concrete with superior strength and durability than conventional structural concrete, however, most of the materials used in its production come from finite natural sources, such as natural aggregates. Thus advances in concrete technology lead to the search for alternative materials that provide improvements in concrete properties while at the same time collaborating with sustainability practices in construction. In this study the influence of the incorporation of tire rubber waste on the mechanical properties of high performance concrete was discussed. The rubber waste from the tire retreading process was used in partial substitution of the fine aggregate (sand) in the percentages of 7.5%, 15% and 30% with respect to the mass of the sand. For the characterization of the concrete the following tests were carried out: Water absorption, void index, specific density, compressive strength, flexural tensile strength, modulus of elasticity and microscopy analysis. The incorporation of rubber as aggregate in high performance concrete proved to be promising for the production of a structural concrete with special characteristics, besides collaborating with the proper disposal of waste tires.