Reference | Presenter | Authors (Institution) | Abstract |
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17-013 | Iranel de las Nieves Gonzalez | Gonzalez, I.d.(Universidade do Vale do Paraíba); dos Santos, K.W.(Universidade do Vale do Paraíba); Oliveira, I.R.(Universidade do Vale do Paraíba); Pandolfelli, V.C.(Universidade Federal de São Carlos); | The scaffolds provides a temporary support for the load application of in vivo forces during the process of bone regeneration. It should have three-dimensional architecture and be highly porous, with an interconnected network of pores for the cell / tissue growth and the transport of nutrients and metabolic residues. It should have mechanical properties similar to the local tissue, and be easy to manufacture in different shapes and sizes. In this work, scaffolds were produced with calcium aluminate as base using the polymeric sponge replication technique. The influence of calcium aluminate percent weight (65, 63, 60 and 55%) and addition of alumina, zirconia, zinc oxide, hydroxyapatite or tricalcium phosphate (4% w) was studied. After thermal treatment at 700oC, the scaffold microstructure was characterized using MEV, and pore size and distribution by mercury porosimetry. 4%-w zirconia and 4%-w zinc oxide (with 55% and 60% -w calcium aluminate) give highest porosity values (60%) and produced the best substrate, presenting interconnected pores of sizes between 150-300 ?m. |
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